Met 500 Mg

Metformin 500 mg (Met 500) is an oral medication prescribed for the management of type 2 diabetes mellitus. It belongs to the class of drugs called biguanides, which work by improving blood sugar control in adults and children over 10 years old.

Key Features:

• Active Ingredient: Metformin Hydrochloride 500 mg
• Mechanism of Action:
  • Decreases glucose production in the liver.
  • Reduces glucose absorption in the intestine.
  • Enhances insulin sensitivity by increasing peripheral glucose uptake and utilization.
• Indications:
  • Management of type 2 diabetes as monotherapy or in combination with other oral antidiabetic agents or insulin.
  • Often prescribed as part of a comprehensive treatment plan, including diet and exercise.

Dosage and Administration:

• Recommended Dosage:
  • Typically, 500 mg taken once or twice daily with meals to reduce gastrointestinal side effects.
  • Dosage adjustments may be made based on glycemic response.
• Maximum Dose: 2,500 mg per day in divided doses.

Common Side Effects:

• Nausea, vomiting, diarrhea, abdominal discomfort, and metallic taste.
• Risk of lactic acidosis, though rare, is a serious side effect.

Warnings and Precautions:

• Not recommended for patients with severe renal impairment (eGFR <30 mL/min/1.73 m²).
• Use with caution in conditions that predispose to hypoxia or dehydration.
• Avoid excessive alcohol consumption to reduce the risk of lactic acidosis.

Storage:

• Store at room temperature (20°C to 25°C or 68°F to 77°F).
• Protect from moisture and heat.

Always consult a healthcare professional for personalized medical advice.